Invasive tests were the first to be used in the diagnosis of H. The traditional division between invasive and noninvasive techniques will be followed. The aim of this article is to review the current status of these methods and their application, highlighting the important progress which has been made in the past decade. pylori infection are performed in microbiology laboratories. Most of the many different techniques involved in diagnosis of H. pylori infection, effective diagnostic methods including susceptibility testing are mandatory. In the history of Nobel prizes, this is only the third time that the discovery of a bacterium has been acknowledged ( 358).įor the correct management of peptic ulcer disease and gastric MALT lymphoma, as well as obtaining information on a wide range of diseases associated with H. pylori and its role in stomach diseases was recognized in 2005 by the attribution of the Nobel Prize in Physiology or Medicine to B. The public health importance of the discovery of H. While sufficient proof is lacking for the most common gastric cancer, i.e., gastric adenocarcinoma, numerous data have highlighted the essential role of the villain ( 335). The rare gastric mucosa-associated lymphoid tissue (MALT) lymphoma is the best example for which most of Bradford Hill's criteria of causality have been fulfilled, including remission of the cancer after a successful eradication of H. pylori, must be treated with antibiotics ( 131a, 295a).įurthermore, the possibility emerged that this bacterium could be the trigger of various malignant diseases of the stomach and it is now a model for chronic bacterial infections causing cancer. It is now well accepted that the most common stomach disease, peptic ulcer disease, is an infectious disease, and all consensus conferences agree that the causative agent, H. The discovery of Helicobacter pylori in 1982 ( 565) was the starting point of a revolution concerning the concepts and management of gastroduodenal diseases.
0 kommentar(er)
